Molecular Validation of Putative Antimicrobial Peptides for Improved Human Immunodeficency Virus Diagnostics via HIV Protein P24
نویسندگان
چکیده
منابع مشابه
Selection of recombinant, library-derived antibody fragments against p24 for human immunodeficiency virus type 1 diagnostics.
By application of combinatorial library technology, we generated the first recombinant antibody fragments directed against the major capsid protein p24 of human immunodeficiency virus type 1 (HIV-1). A library of single-chain Fv fragments (scFvs) was constructed by using the antibody variable-region (V) genes of B cells derived from the spleen of a viral lysate-immunized mouse. Antibodies were ...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2015
ISSN: 2328-8957
DOI: 10.1093/ofid/ofv133.262